<\/p>\n
CNN’in haberine g\u00f6re, bilim insanlar\u0131, ke\u015fiften elde edilen bilgilerin, insan beslenmesindeki de\u011fi\u015fikliklerin, \u00e7\u00fcr\u00fcklerin ve di\u015f eti hastal\u0131klar\u0131n\u0131n yayg\u0131nla\u015fmas\u0131na etkisini anlamaya yard\u0131mc\u0131 olabilece\u011fini belirtti.<\/p>\n
\u0130rlanda’n\u0131n Limerick kentindeki kire\u00e7ta\u015f\u0131 ma\u011faras\u0131nda, 1993-1996 y\u0131llar\u0131nda yap\u0131lan arkeolojik kaz\u0131larda, insan di\u015f ve kemik kal\u0131nt\u0131lar\u0131 bulundu.<\/p>\n
Bilim insanlar\u0131, milattan \u00f6nce 2280-2140 y\u0131llar\u0131nda Bronz \u00c7a\u011f\u0131’ndaki insana ait oldu\u011fu ortaya \u00e7\u0131kan iki di\u015f \u00fczerinde ara\u015ft\u0131rma yapt\u0131.<\/p>\n
Ara\u015ft\u0131rman\u0131n ba\u015f yazar\u0131, Dublin Trinity College Genetik B\u00f6l\u00fcm\u00fc \u00d6\u011fretim \u00dcyesi Dr. Lara Cassidy, di\u015flerden birinde bol miktarda, \u00e7\u00fcr\u00fcklere yol a\u00e7an a\u011f\u0131z bakterisi “Streptococcus Mutans’\u0131n (S. Mutans)” bulundu\u011funu a\u00e7\u0131klad\u0131.<\/p>\n
Cassidy, di\u015flerde \u00e7\u00fcr\u00fcmeye ve DNA bozulumuna yol a\u00e7an bu bakterinin, asit \u00fcreten do\u011fas\u0131 nedeniyle iyi korunamad\u0131\u011f\u0131ndan genomik kay\u0131tlarda nadiren bulundu\u011funu kaydetti.<\/p>\n
Ara\u015ft\u0131rmada, di\u011fer antik buluntularda da di\u015f \u00e7\u00fcr\u00fckleri g\u00f6zlemlendi\u011fi ancak “S. Mutans” t\u00fcr\u00fc bakterilerin, g\u00fcneybat\u0131 Fransa’da bulunan ve milattan \u00f6nce 3400-2900 y\u0131llar\u0131na tarihlenen eski bir Neolitik di\u015f ve \u0130skandinav Mezolitik d\u00f6neminden kalan ve milattan \u00f6nce 9890-9540 y\u0131llar\u0131na tarihlenen \u00e7i\u011fnenmi\u015f kara sak\u0131z buluntusu gibi nadir \u00f6rneklerde, yaln\u0131zca \u00e7ok d\u00fc\u015f\u00fck miktarlarda ke\u015ffedildi\u011fi belirtildi.<\/p>\n
Cassidy, ara\u015ft\u0131rmac\u0131lar\u0131n, bakterilerin arkeolojik kaz\u0131larda bulunan antik di\u015flerde bug\u00fcnk\u00fc kadar yayg\u0131n olmad\u0131\u011f\u0131n\u0131 d\u00fc\u015f\u00fcnd\u00fc\u011f\u00fcn\u00fc belirterek, o d\u00f6nemlerde t\u00fcketilen besinlerin daha az rafine \u015feker ve i\u015flenmi\u015f g\u0131da i\u00e7erdi\u011fini s\u00f6yledi.<\/p>\n
Yakla\u015f\u0131k 10 bin y\u0131l \u00f6nce insan hayat\u0131na tar\u0131m\u0131n girmesiyle \u00f6nemli bir beslenme de\u011fi\u015fiminin g\u00f6r\u00fcld\u00fc\u011f\u00fcn\u00fc kaydeden Cassidy, bu\u011fday ve arpa gibi tah\u0131llar\u0131n yeti\u015ftirildi\u011fi antik d\u00f6nemlerde di\u015f \u00e7\u00fcr\u00fcklerinin s\u0131k g\u00f6r\u00fcld\u00fc\u011f\u00fcn\u00fc, son birka\u00e7 y\u00fczy\u0131lda ise \u015fekerin yayg\u0131nla\u015fmas\u0131yla beslenme al\u0131\u015fkanl\u0131klar\u0131n\u0131n da de\u011fi\u015fti\u011fini vurgulad\u0131.<\/p>\n
Cassidy, Bronz \u00c7a\u011f\u0131’ndan kalan di\u015fteki “S. Mutans”\u0131n bug\u00fcnk\u00fc \u00f6rnekleriyle kar\u015f\u0131la\u015ft\u0131r\u0131lmas\u0131n\u0131n, bakterinin zarara yol a\u00e7ma yetene\u011finin \u015feker ve tah\u0131l\u0131n yayg\u0131nla\u015fmas\u0131yla daha da artt\u0131\u011f\u0131n\u0131 ortaya koydu\u011funu s\u00f6yledi.<\/p>\n
Ara\u015ft\u0131rmac\u0131, “Ge\u00e7ti\u011fimiz birka\u00e7 y\u00fczy\u0131l (insan beslenmesinde) \u00e7\u0131lg\u0131nca de\u011fi\u015fime tan\u0131k oldu. Bu nedenle bunun mikrobiyomu (insan derisinde ve v\u00fccudunun \u00fczerinde do\u011fal olarak ya\u015fayan bakteriler gibi mikroorganizmalar), sadece a\u011f\u0131z de\u011fil ayn\u0131 zamanda ba\u011f\u0131rsak mikrobiyomunu nas\u0131l etkiledi\u011fini anlamak, son birka\u00e7 y\u00fczy\u0131lda Bat\u0131 toplumlar\u0131nda veya Bat\u0131l\u0131la\u015fm\u0131\u015f toplumlarda baz\u0131 hastal\u0131klar\u0131n neden bu kadar yayg\u0131n hale geldi\u011fini anlamam\u0131za bir miktar yard\u0131mc\u0131 olabilir.” ifadelerini kulland\u0131.<\/p>\n
Ara\u015ft\u0131rmaya dahil olmayan, Londra Do\u011fa Tarihi M\u00fczesi \u0130nsan Geli\u015fimi Ara\u015ft\u0131rma Merkezi \u00e7al\u0131\u015fan\u0131 Dr. Louise Humphrey ise antik ve modern “S. Mutans”\u0131n kar\u015f\u0131la\u015ft\u0131rmal\u0131 analizinin, son birka\u00e7 y\u00fczy\u0131lda artan \u015feker t\u00fcketimiyle ba\u011flant\u0131l\u0131 b\u00fcy\u00fck bir de\u011fi\u015fikli\u011fi ortaya \u00e7\u0131kard\u0131\u011f\u0131n\u0131 ve 19. y\u00fczy\u0131lda rafine \u015fekerin yayg\u0131nla\u015fmas\u0131yla daha y\u00fcksek \u00e7\u00fcr\u00fck oranlar\u0131 g\u00f6r\u00fcld\u00fc\u011f\u00fcne dair \u00f6nceki ara\u015ft\u0131rmalar\u0131 destekledi\u011fini bildirdi.<\/p>\n
Dublin Trinity College’dan yap\u0131lan a\u00e7\u0131klamada ise incelenen iki di\u015fte, antik genom kay\u0131tlar\u0131nda daha yayg\u0131n g\u00f6r\u00fclen ve di\u015f eti hastal\u0131\u011f\u0131na yol a\u00e7an “Tannerella Forsythia (T. Forsythia)” bakterisinin DNA \u00f6rne\u011finin de bulundu\u011fu belirtildi.<\/p>\n
Ara\u015ft\u0131rmac\u0131lar, incelenen di\u015flerde bakterinin iki farkl\u0131 t\u00fcr\u00fcn\u00fc bulurken, bug\u00fcn s\u00f6z konusu bakterinin sadece bir t\u00fcr\u00fcne rastland\u0131\u011f\u0131 kaydedildi. Ara\u015ft\u0131rmada, antik mikrobiyomlar\u0131n bug\u00fcne nazaran \u00e7ok daha fazla biyolojik \u00e7e\u015fitlilik i\u00e7erdi\u011fi ve bunun kayb\u0131n\u0131n insan sa\u011fl\u0131\u011f\u0131 \u00fczerinde olumsuz etkileri olabilece\u011fi vurguland\u0131.<\/p>\n
Ara\u015ft\u0131rma “Molecular Biology and Evolution” dergisinde yay\u0131mland\u0131.<\/p>\n