<\/p>\n
Gazi \u00dcniversitesi T\u0131p Fak\u00fcltesi Onkoloji \u00d6\u011fretim \u00dcyesi Prof. Dr. U\u011fur Co\u015fkun, yurt d\u0131\u015f\u0131nda yap\u0131lan \u00e7al\u0131\u015fma sonucu meme ve ba\u011f\u0131rsak t\u00fcm\u00f6r\u00fcnde kanserin yay\u0131l\u0131m\u0131n\u0131 h\u0131zland\u0131ran “ZEB-1” adl\u0131 proteinin tespit edildi\u011fini bildirirken, “Meme kanserine ili\u015fkin yap\u0131lan \u00e7al\u0131\u015fma sonucunda ise ZEB-1 proteinin meme kanseri t\u00fcm\u00f6r\u00fcn\u00fcn kemi\u011fe daha s\u0131k metastaz yapt\u0131\u011f\u0131 ortaya kondu” dedi.<\/p>\n
T\u00fcm\u00f6r h\u00fccrelerinde bulunan ZEB-1 proteinin meme kanseri h\u00fccrelerinin esnekli\u011fini art\u0131rd\u0131\u011f\u0131 ve olu\u015fan proteinin, kanserin yay\u0131lmas\u0131yla ili\u015fkili olabilece\u011finin g\u00f6sterildi\u011fini belirten Co\u015fkun, bu proteinin olmad\u0131\u011f\u0131 kanser t\u00fcm\u00f6rlerinde, kanserin kemi\u011fe yay\u0131lma olas\u0131l\u0131\u011f\u0131n\u0131n daha d\u00fc\u015f\u00fck oldu\u011funun saptand\u0131\u011f\u0131n\u0131 kaydetti.<\/p>\n
Prof. Dr. Co\u015fkun, yurt d\u0131\u015f\u0131nda yap\u0131lan ba\u015fka bir \u00e7al\u0131\u015fmada, ba\u011f\u0131rsak kanserinde de ayn\u0131 proteinin tespit edildi\u011fini aktararak, “ZEB-1 proteini ortadan kald\u0131r\u0131l\u0131rsa hastal\u0131\u011f\u0131n tekrar etmesinin \u00e7ok daha d\u00fc\u015f\u00fck oranda olaca\u011f\u0131 saptanm\u0131\u015f durumda. Meme ve ba\u011f\u0131rsak kanseri ve di\u011fer kanser t\u00fcrlerinde buna y\u00f6nelik \u00e7al\u0131\u015fmalar devam ediyor, ileride bunlarla ilgili geli\u015ftirilecek ila\u00e7lar, bize yol g\u00f6sterebilir.” a\u00e7\u0131klamas\u0131n\u0131 yapt\u0131.<\/p>\n
Ba\u011f\u0131rsak kanserinde tespit edilen “ZEB-1” proteininin, kanser h\u00fccrelerinin di\u011fer organlara yay\u0131lmas\u0131n\u0131 kolayla\u015ft\u0131rd\u0131\u011f\u0131n\u0131 aktaran Co\u015fkun, “Dolay\u0131s\u0131yla bu protein varsa, onun oldu\u011fu kanser h\u00fccreleri daha h\u0131zl\u0131 \u015fekilde yay\u0131lma g\u00f6sterebiliyor. Bu, t\u00fcm\u00f6r\u00fcn kendi geli\u015ftirdi\u011fi bir protein. Yap\u0131s\u0131 itibariyle e\u011fer bu proteini geli\u015ftiriyorsa t\u00fcm\u00f6r\u00fcn davran\u0131\u015f \u00f6zelliklerini de belirlemi\u015f oluyor.” diye konu\u015ftu.<\/p>\n
Co\u015fkun, ba\u011f\u0131rsak kanserinde “ZEB-1” proteine ili\u015fkin yap\u0131lan \u00e7al\u0131\u015fmada, proteinin ortadan kald\u0131r\u0131lmas\u0131 durumundaki geli\u015fmelerin de incelendi\u011fini s\u00f6yleyerek, “Bu proteinin ortadan kalkt\u0131\u011f\u0131 durumda ba\u011f\u0131rsak kanserinin yay\u0131lmas\u0131 ve ba\u015fka organlara s\u0131\u00e7ramas\u0131n\u0131n engellendi\u011fi, hastalar\u0131n ya\u015fam s\u00fcrelerinin daha iyi oldu\u011fu ortaya konuldu. Bununla ilgili \u00e7al\u0131\u015fmalar yo\u011funla\u015fm\u0131\u015f durumda. Bu proteinin aktivitesini ortadan kald\u0131racak ila\u00e7lar geli\u015ftirilebilir.” dedi. <\/p>\n
Yurt d\u0131\u015f\u0131ndaki \u00e7al\u0131\u015fmalarda \u00f6ce h\u00fccre k\u00fclt\u00fcrlerinin, sonra hayvan \u00e7al\u0131\u015fmalar\u0131 yap\u0131laca\u011f\u0131n\u0131 aktaran Co\u015fkun, “Daha sonra da insan \u00e7al\u0131\u015fmalar\u0131na ge\u00e7ilecek. Bunun i\u00e7in biraz daha zaman var. ZEB-1 proteinin aktifli\u011fi ortadan kald\u0131r\u0131l\u0131rsa, kanserin yay\u0131lmas\u0131 \u00f6nlenirse hasta zaten tamamen iyile\u015fmi\u015f oluyor. Yo\u011fun bir \u015fekilde bunlarla ilgili ara\u015ft\u0131rmalar devam ediyor.” a\u00e7\u0131klamas\u0131na yer verdi.<\/p>\n