Avrupa T\u0131p Uzmanlar\u0131 Birli\u011fi Nadir ve Tan\u0131s\u0131z Hastal\u0131klar Komisyonu Ba\u015fkan Yard\u0131mc\u0131s\u0131 Prof. Dr. Serdar Ceylaner, gluten hassasiyetinin baz\u0131 ki\u015filerde migren ataklar\u0131n\u0131 tetikleyebildi\u011fini, gluten kesildi\u011finde \u015fikayetlerin de azald\u0131\u011f\u0131n\u0131 bildirdi.<\/p>\n
T\u0131bbi Genetik Uzman\u0131 Prof. Dr. Ceylaner, AA muhabirine yapt\u0131\u011f\u0131 a\u00e7\u0131klamada, son d\u00f6nemde baz\u0131 hastalarda migrenle glutenin ili\u015fkisini ispatlayan \u00e7al\u0131\u015fmalar\u0131n yap\u0131ld\u0131\u011f\u0131n\u0131 kaydetti.<\/p>\n
![\"\"](\"https:\/\/www.aa.com.tr\/uploads\/userFiles\/9c85db40-ef31-40fe-a989-05c7e506d5d0\/02_2024%2F11022024%2Fserdar1_.jpg\"\/)
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Gluten hassasiyetinin, ba\u011f\u0131\u015f\u0131kl\u0131k sistemiyle ilgili otoimm\u00fcn hastal\u0131klardan biri oldu\u011funu, migrenin de bu hastal\u0131klara e\u015flik eden bir durum olarak ortaya \u00e7\u0131kabildi\u011fini belirten Ceylaner, “Elbette bu, her gluten hassasiyeti olanda migren ortaya \u00e7\u0131kar anlam\u0131na gelmiyor. Ancak baz\u0131 hastalarda bu tablo ya\u015fanabiliyor.” bilgisini payla\u015ft\u0131.<\/p>\n
Prof. Dr. Ceylaner, gluten hassasiyeti kaynakl\u0131 migrenin tespiti i\u00e7in ay\u0131rt edici baz\u0131 testlerin yap\u0131lmas\u0131 gerekti\u011fini vurgulayarak, “Bize en \u00e7ok ‘migren hastas\u0131y\u0131m o zaman do\u011frudan gluteni keseyim mi’ gibi sorular geliyor. Buna cevab\u0131m\u0131z, ‘hay\u0131r’. \u00d6nce migrenin sebebinin anla\u015f\u0131lmas\u0131 gerekiyor. \u00d6rne\u011fin, baz\u0131 epilepsi t\u00fcrleri, damar hastal\u0131klar\u0131 da migren gibi belirtilerle seyredebiliyor.” diye konu\u015ftu.<\/p>\n
“Genetik zemin s\u00f6z konusu”<\/h3>\n
Yeni genetik teknolojiler, analizler sayesinde migren tan\u0131s\u0131n\u0131n ve ortaya \u00e7\u0131kma nedeninin daha kolay anla\u015f\u0131labildi\u011fini aktaran Ceylaner, s\u00f6zlerini \u015f\u00f6yle s\u00fcrd\u00fcrd\u00fc:<\/p>\n
“Gluten hassasiyeti dahil b\u00fct\u00fcn otoimm\u00fcn hastal\u0131klarda altta bir genetik zemin s\u00f6z konusudur. Bu genetik zemin nedeniyle ba\u011f\u0131\u015f\u0131kl\u0131k sistemi v\u00fccutta kendi h\u00fccrelerine az da olsa zarar vermeye ba\u015flar. Bazen tek ba\u015f\u0131na glutene kar\u015f\u0131 hassasiyet, bazen de birka\u00e7 fakt\u00f6r\u00fcn bir araya geldi\u011fi durumlar olu\u015fabiliyor. Dolay\u0131s\u0131yla altta yatan durumu iyi saptay\u0131p, buna g\u00f6re bir tedavi plan\u0131 olu\u015fturmak \u00e7ok \u00f6nemli.”<\/p>\n
“Gluten hassasiyeti ile \u00e7\u00f6lyak birbirine kar\u0131\u015ft\u0131r\u0131l\u0131yor”<\/h3>\n
Prof. Dr. Serdar Ceylaner, gluten hassasiyeti ile \u00e7\u00f6lyak hastal\u0131\u011f\u0131n\u0131n birbirine kar\u0131\u015ft\u0131r\u0131ld\u0131\u011f\u0131na i\u015faret ederek, \u00e7\u00f6lya\u011f\u0131n \u00e7ocukluk \u00e7a\u011f\u0131nda g\u00f6r\u00fclen, ciddi geli\u015fme gerili\u011fi, boy k\u0131sal\u0131\u011f\u0131 gibi problemlere yol a\u00e7an a\u011f\u0131r bir hastal\u0131k oldu\u011funu vurgulad\u0131.<\/p>\n
Gluten hassasiyetinde ise gluten t\u00fcketiminin ba\u011f\u0131\u015f\u0131kl\u0131k sistemini etkiledi\u011fini anlatan Ceylaner, “Gluten hassasiyeti, ba\u015fta ba\u011f\u0131rsak olmak \u00fczere v\u00fccuttaki bir\u00e7ok sistemde soruna yol a\u00e7\u0131yor, migren de bunlardan biri. Ayr\u0131ca y\u00fczde sivilce, v\u00fccutta a\u011fr\u0131, fibromiyalji gibi farkl\u0131 klinik bulgular da ortaya \u00e7\u0131kabiliyor.” dedi.<\/p>\n
“Migren hastal\u0131k de\u011fil, bulgu”<\/h3>\n
Migrenle ilgili g\u00fcncel \u00e7al\u0131\u015fmalar\u0131 aktaran Ceylaner, “T\u0131bbi genetik uzmanlar\u0131n\u0131n, yeni t\u0131bb\u0131n yakla\u015f\u0131m\u0131 ‘migren bir hastal\u0131k de\u011fil, bulgu. O bulgunun alt\u0131ndaki sebepleri ara\u015ft\u0131r\u0131p tespit etti\u011finizde, tedavi etmeniz de kolayla\u015f\u0131yor.” de\u011ferlendirmesinde bulundu.<\/p>\n
Uluslararas\u0131 alanda 2019’da haz\u0131rlanan “Gluten \u0130li\u015fkili Hastal\u0131klar\u0131n Tan\u0131s\u0131, Takibi ve Tedavisi” konulu rehberde, \u00e7\u00f6lya\u011f\u0131n yan\u0131 s\u0131ra gluten hassasiyeti sonucu ortaya \u00e7\u0131kan bir\u00e7ok hastal\u0131\u011fa da yer verildi\u011fini an\u0131msatan Ceylaner, gluten hassasiyetinin, gebelik kay\u0131plar\u0131, migren, alerji, cilt hassasiyeti gibi bir\u00e7ok rahats\u0131zl\u0131ktaki etkisinin rehberde payla\u015f\u0131ld\u0131\u011f\u0131n\u0131 s\u00f6yledi.<\/p>\n
Ceylaner, “Gluten hassasiyetinde, genetik HLA testlerinin yap\u0131lmas\u0131, risk alt\u0131nda olanlara da 6 haftal\u0131k bir diyet uygulanmas\u0131 ve bunun sonunda bulgular\u0131nda de\u011fi\u015fiklik olup olmad\u0131\u011f\u0131n\u0131n belirlenmesi \u00f6nemli. Ki\u015finin bulgular\u0131nda azalma varsa, iki sonucu bir araya getirerek, ‘\u00e7\u00f6lyak olmayan gluten hassasiyeti’ tan\u0131s\u0131n\u0131 koyuyoruz.” ifadesini kulland\u0131.<\/p>\n
“‘Gluteni hayat\u0131m\u0131zdan \u00e7\u0131karal\u0131m’ anlam\u0131na gelmiyor”<\/h3>\n
T\u0131bbi Genetik Uzman\u0131 Prof. Dr. Serdar Ceylaner, gluten hassasiyeti kaynakl\u0131 migren ataklar\u0131 ya\u015fayan \u00e7ok say\u0131da hastayla kar\u015f\u0131la\u015ft\u0131klar\u0131na de\u011finerek, \u015f\u00f6yle devam etti:<\/p>\n
“Gluten hassasiyeti saptad\u0131\u011f\u0131m\u0131z ki\u015filerde, gluteni kesti\u011fimizde ki\u015filerin migren bulgular\u0131n\u0131n azald\u0131\u011f\u0131na veya kayboldu\u011funa, ayr\u0131ca ba\u011f\u0131rsak s\u0131k\u0131nt\u0131lar\u0131, \u00f6dem, kronik yorgunluk gibi \u015fikayetlerin azald\u0131\u011f\u0131na ili\u015fkin geri d\u00f6n\u00fc\u015fler al\u0131yoruz. Bug\u00fcne kadar \u00e7ok say\u0131da hastada bu tabloyu g\u00f6rd\u00fck.<\/p>\n
Ancak bu, ‘hepimiz gluteni hayat\u0131m\u0131zdan \u00e7\u0131karal\u0131m’ anlam\u0131na gelmiyor. Bu sadece gluten hassasiyetinde ge\u00e7erli olan bir durum. Gluten, \u00f6z\u00fcnde sa\u011fl\u0131k a\u00e7\u0131s\u0131ndan \u00e7ok \u00f6nem verdi\u011fimiz tah\u0131llarda yer alan bir protein. Bu\u011fday\u0131n i\u00e7indeki her \u015feye ihtiyac\u0131m\u0131z var ve bu nedenle gluten hassasiyeti olan ki\u015filerde yulaf \u00fcr\u00fcnleriyle bu a\u00e7\u0131\u011f\u0131 kapatmaya \u00e7al\u0131\u015f\u0131yoruz.”<\/p>\n